How serious are the crashes where this part is cited?

In NHTSA's crash sample (CRSS, 2019–2022), 4.0% of police-reported crashes that cite tires ended in a serious or fatal injury, against 2.9% of all police-reported crashes. A crash that cites a system is not necessarily a crash that system caused.

How badly people were hurt in crashes citing tires, against all crashes

What it shows: No Apparent Injury is the largest at 69.3%, followed by Possible Injury at 13.3%; the smallest shown is Fatal Injury at 1.1%.

Source: NHTSA Crash Report Sampling System (CRSS), 2019–2022 pooled · data from 2022

Data and chart by CalcScrape: Tire Cost Calculator